Strategic districts in Brussels to establish your business

Brussels stands out as a key business hub in Europe. The Belgian capital, home to major European institutions, offers a dynamic economic environment, attractive tax incentives and infrastructure fully geared toward doing business.But where should you set up your office to benefit from a prestigious address, attract top talent and optimize your operations?In this article, discover the most strategic districts in Brussels for your company, their unique strengths, and how Mesh-Immo can help you secure the ideal workspace.

The North District: Belgium’s largest business hub

A dynamic real estate market

The North District (Quartier Nord) is Belgium’s second largest business area, after the European Quarter (Leopold District).It spans nearly 1.2 million m² of office space, drawing in a wide range of international organizations, multinational headquarters and institutions.Whether you are a start-up, SME or large corporation, you’ll find flexible coworking spaces, traditional premium offices and fully equipped meeting facilities.

Exceptional accessibility

Connected by multiple metro, bus and train lines, and close to major roads, the North District offers seamless mobility for employees and visitors. It’s the ideal choice for companies looking to simplify daily commutes.

Premium services and amenities

Restaurants, shopping centers, sports facilities… this district is more than just offices. It’s a vibrant place that enhances employees’ quality of life and productivity.

Modern, sustainable office spaces

Many buildings in the North District are undergoing renovations to achieve BREEAM certifications, meeting high standards of energy efficiency, water management and sustainable materials.

A profitable long-term investment

While rental rates here may seem higher, it’s the price for enhanced visibility and a stimulating business environment, right at the heart of Belgium and Europe’s economic activity.

The European Quarter: political and economic heart of Europe

Close to European decision-makers

If your company aims to be near European policy-makers, this is the place to be. The area hosts the European Commission, European Parliament and the Council of the EU, naturally attracting consultancies, NGOs and global enterprises.

High-end offices with exemplary sustainability

Many buildings here, such as the M10 at 10 Montoyer Street, boast certifications like WELL, BREEAM Outstanding, Fossil Fuel Free and CO2-neutral A+, ensuring a premium, eco-friendly work environment.

A vibrant international ecosystem

It’s a cosmopolitan district where institutions, think tanks, innovative start-ups and large groups meet — ideal for networking and staying ahead of regulatory changes.

Central Station: a national and international hub

A strategic rail network

Located between Brussels’ Grand Place and the Royal Park, Central Station is one of the country’s primary transport hubs, offering rapid connections to major Belgian and European cities.

Attract top talent and simplify meetings

Choosing an office near Central Station gives your employees and partners direct access, whether by train, metro, bus or taxi. It saves time and makes your business more appealing.

Rogier: a modern, well-connected business district

Iconic towers and dynamic coworking spaces

Over the years, Rogier has evolved into a recognized business center, with modern towers such as the Dexia Tower (now Rogier Tower) and a wide range of coworking spaces that foster innovation.

An attractive urban lifestyle

Restaurants, shopping centers and cultural venues make Rogier a place where work and life blend seamlessly, crucial for employee well-being.

Rue Neuve: Brussels’ retail hotspot

Constant foot traffic and a diverse clientele

With thousands of visitors daily, Rue Neuve is Belgium’s busiest shopping street. For retail businesses or showrooms, it’s a strategic location that guarantees visibility and sales.

Collaboration and synergy

The high concentration of stores naturally creates joint promotions, events and themed displays, drawing even more customers.

The Pentagon: historical and cultural heart of Brussels

A prestigious district in the city center

The Pentagon offers a wide range of modern office spaces, surrounded by historical buildings, museums and cultural landmarks. It’s ideal for companies seeking to combine prestige, accessibility and quality of work life.

Always lively and easily accessible

Close to Brussels Central, North and South stations, well-served by metro, tram and bus, the Pentagon is buzzing day and night with restaurants, bars and green spaces.

Why choose Mesh-Immo to establish your business in Brussels?

As a real estate agency specialized in commercial property, Mesh-Immo puts its deep knowledge of the Brussels market at your service to:

✅ Select the best offices tailored to your needs (size, certifications, accessibility)✅ Negotiate the best lease or purchase conditions✅ Support your long-term growth by adapting your spaces as your business evolves.

Contact us today for personalized guidance.

FAQ – All about Brussels’ business districts

What is the most sought-after area for businesses in Brussels?

It depends on your industry. Multinationals and institutions often choose the European Quarter, while the North District is popular for its modern office spaces. Rogier and Central Station attract companies thanks to their excellent accessibility.

Why set up close to European institutions?

Being near the Parliament and the European Commission means direct access to decision-makers, strategic relationships and stronger international visibility.

What are the average office rental prices in Brussels?

They vary by district: typically €170 to €280/m²/year for premium offices in the European Quarter and the North District.

Which certifications should you look for in sustainable offices?

Look for offices certified with BREEAM, WELL or CO2-neutral A+, which guarantee environmental responsibility and employee well-being.

Conclusion: Brussels, a springboard for your business

Setting up in Brussels means choosing an international capital that is dynamic, well-connected and committed to sustainability.With Mesh-Immo, easily find the district and workspace that will make the difference for your team and your brand.👉 Contact us now to explore our office spaces in these strategic districts.